February 21, 2024


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NanobOx named One to Watch at 2022 Big Ideas showcase

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NanobOx named One to Watch at 2022 Big Ideas showcase

This year’s Large Thoughts included an injectable gel remedy for knee osteoarthritis, AI-driven online video summarisation, a clinical unit to deal with dry eyes and a resource to decreased carbon emissions.

NanobOx has gained this year’s Massive Thoughts competition for tech commence-ups run by Company Eire. It was 1 of 12 trader-ready get started-ups that pitched their business enterprise versions at an event these days (24 November).

NanobOx was pitched by Dr John Favier, a serial entrepreneur who potential customers the begin-up as CEO. Favier founded NovaUCD spin-out NanobOx alongside with Dr Mohammad Ghaani.

The duo have formulated a highly electricity-productive know-how to oxygenate water applying nanobubbles. Many professional bioprocesses have to have oxygen concentrations in procedure waters to be persistently preserved. This can be a substantial running price tag for a approach that can be vital to productiveness.

In aquaculture, or the farming of fish shares, for case in point, the power price of oxygenation can be the second highest expense soon after feed. It can characterize 60personal computer to 70laptop of working prices in biological wastewater treatment method.

Producing nanobubbles is especially energy intense but, with novel, patented know-how, NanobOx has managed to minimize the energy essential to do so. Its nanobubble generators can be solar or battery-driven, and with no going areas they are uncomplicated to clean and preserve. The corporation statements its technologies is remarkably scalable and can oxygenate h2o at substantial flowrates.

Fada Health care wins Viewers’ Alternative

Now in its 14th calendar year, Big Ideas held its 2022 pitch occasion in entrance of a dwell audience in Croke Park as very well as a virtual viewers on the internet.

Large Concepts showcases deep-tech get started-up innovation emerging from increased instruction institutes. It offers founders with direct obtain to investors and an chance to unveil their business enterprise concept.

The Massive Tips pitch teams had been competing for the 1 to Watch Award, which was made a decision by a judging panel. The dwell and on the web audiences also picked the winner of the Viewers’ Alternative Award.

This year, that award went to Fada Professional medical, which is on a mission to strengthen insulin delivery for men and women residing with kind 1 diabetic issues. To do this, Fada Clinical has developed a novel diffusion engineering that can extend the use-time of infusion-established cannulas, supporting consistent long-phrase insulin pump use.

Supporting deep-tech

All 12 start off-ups competing at the celebration had a few minutes to promote their innovations and business propositions to the invited in-person and on the net viewers created up of the Irish analysis and expenditure communities and the broader start off-up ecosystem.

Minister of Condition for Trade Advertising, Digital and Organization Regulation at the Section of Company Trade and Employment Dara Calleary, TD, mentioned that Ireland has just one of the “most vibrant and collaborative commercialisation ecosystems in the world”.

He also emphasised the relevance of Point out funding for modern firms. “As these founders experience a more complicated start-up funding environment, it is essential to maintain and help their advancement, and instruments this sort of as the Disruptive Technological innovation Innovation Fund play a important role in addressing possible funding gaps for deep-tech start out-ups.”

Company Ireland CEO Leo Clancy echoed Calleary’s feedback on funding support. “Given the intense global headwinds that Irish enterprises are facing, it has by no means been extra essential to champion the bravery and ambition of Irish founders, as their spirit and travel are the cornerstones of our neighborhood and nationwide economies.

“Enterprise Ireland is committed to more accelerating entrepreneurship in Eire and today’s party is an great example of this, with the conversation amongst investors, larger education and learning institutes and our have help groups providing these 12 ambitious founders with an opportunity to get their firms to the upcoming amount.”

Go through on for facts on the other 10 start out-ups pitching their Significant Thoughts.

Darwin & Goliath

This Trinity University Dublin spin-out from the Adapt analysis centre delivers carbon calculators that categorise transaction knowledge to figure out carbon hotspots and offer suggestions to lessen carbon emissions. The technological know-how enables businesses to calculate and in the long run lessen emissions in procurement by comparing distributors and displaying emissions info to conclusion customers.


An rising College Faculty Dublin (UCD) start-up, Giyst is working with AI and device finding out to create online video summaries to tackle the concerns of information and facts overload and shortening interest spans. It is concentrating on this service at the business enterprise, training and other marketplaces. The purpose is to repurpose written content to generate superior engagement and discovery.


Infraprint’s technologies enables the 3D printing of engineering plastics stronger than any program on the marketplace. This enables the manufacture of large-toughness, lightweight, customised sections in a cost and time-productive way. This technological know-how is specifically practical for production smaller batch elements, for the aerospace and pharmaceutical industries and over and above.

Lia Therapeutics

Next wants-led investigation executed during the BioInnovate fellowship programme at University of Galway and a Commercialisation Fund from UCD, Lia Therapeutics has made Nightleaf, a drug-cost-free, wearable professional medical gadget to take care of dry and sore eyes.


Dr Conor Lynch, a study fellow and team lead at the Nimbus investigation centre in Munster Technological University, has designed a software to automate electrical power cost savings. His company, OPEnS has a grid-linked sensible community method that, utilizing strength market-tracking tariff prediction technologies, has the capacity to optimise based mostly on strength expense, carbon emissions or both equally simultaneously.


Royal College of Surgeons in Eire (RCSI) spin-out Pumpinheart has prototyped a transcatheter implantable diastolic coronary heart pump, PReduction, to address superior stage coronary heart failure. The administration staff has a combine of clinical, engineering and start off-up abilities. Prior to signing up for RCSI, CMO Dr Aamir Hameed was a cardiothoracic surgeon. CEO Donald Hickey is an professional edtech and medtech entrepreneur and CTO Dr Andrew Malone is a medical physicist.


Acquiring previously managed tasks for big multinationals this kind of as Roche, Boston Scientific and Prepare dinner Medical, Dr Alison Liddy, co-Founder of ReleviumBio, has formulated an injectable gel therapy to give excellent reduction and defense from knee osteoarthritis. The corporation is targeting the knee as a first scientific sign and options to lengthen the procedure indications to goal other joints impacted by osteoarthritis, wherever the exact same procedure challenges exist.

TiLT (Transformation in Learning and Teaching)

TiLT has created a training option to make assorted organisations far more inclusive, as a person does not essentially go hand-in-hand with the other. To do this, TiLT focuses not on individual unconscious bias instruction but on shifting the norms all around social interaction in just an organisation.


UniDoodle has established a digital instrument that addresses the issue of student disengagement in course-dependent finding out. Denise O’Grady, who pitched UniDoodle at Big Tips, is a serial edtech entrepreneur acquiring started Way2Spend in 2013. This start out-up was not too long ago offered to Evo Payments, a US-centered payments know-how company.


Age-relevant macular degeneration (AMD) is a neurodegenerative retinal sickness affecting up to 10personal computer of grown ups in excess of 65 years. Vzarii has made gene therapies that concentrate on late-phase dry AMD. These gene remedy systems are the consequence of pioneering exploration from the Farrar crew at the College of Genetics and Microbiology at Trinity School Dublin.

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Added reporting by Elaine Burke

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